Friday, January 31, 2020

Organ Donation Research Paper Example | Topics and Well Written Essays - 1000 words

Organ Donation - Research Paper Example First and most of all, one the most important implications that organ donation has is saving life. Indeed, if one takes a brief look at the statistics, one will be able see that the good which can be done is tremendous. For example, a single organ that is extracted from the body of a person who is dead is able to safe eight people (â€Å"All About Donation†). This is quite an astonishing statistics since given the number of organs that a person is able to donate after death, one single person may save up to fifty people. It is rather obvious that a death of a single person is a tragedy, but if it is able to result the continuation of lives of numerous people, the former gains a new sound to it. That is why a person who donates one’s organs as basically a hero who saves many lives. Another point which should be noted is that the issues of organ donation and saving lives might be viewed from a rather surprising point of view. Thus, one can hardly disagree that life is the best gift that a person can receive. However, in the course of out daily routine people tend to forget about it and that being alive for granted. Moreover, the ability to give life is largely thought to be mystical and is often attributed to deities. In addition to that, if a person could chose what one would like to receive as the ultimate gift, one would definitely choose being immortal.

Thursday, January 23, 2020

Ribozymes Essay -- Biology, Catalytic Molecules, RNA

Ribozymes are catalytic molecules that cleave the ribonucleic acid (RNA) at specific sequences (Gesteland et al. 2006). RNA is the nucleic acid that is made in the process of transcription; when the deoxyribonucleic acid (DNA) anneals, it transcribes itself into a linear stranded molecule called RNA. In order for RNA to synthesise proteins, it requires catalytic enzymes to perform certain chemical reactions. In the past, it was thought that all chemical reactions are catalysed by protein enzymes; however, in the eighties this hypothesis was disproved as Thomas Cech and Sydney Altman discovered that RNA is able to carry out self-catalysing activities which were named as ribozymes because they perform similar functions as the protein enzymes (Jaeger, 1997). Even though, RNA ribozymes lack the functional groups diversity found in protein enzymes, they are able to carry out their own catalytic reactions due to their tendency to fold into a 3D structure and form helices by Watson-Crick ba se pairing role (Kiehntopf et al. 1995). Ribozymes are now play critical role in the understanding of biochemistry, as they have the ability to catalyse some of the most important chemical reactions such as RNA splicing as well as the synthesis of peptides, for instance ribozymes can speed up the phosphoryl transfer chemical reactions by 1011 folds. This review will describe the structure, sources and applications of ribozymes. There are several naturally occurring ribozymes that have been identified to date; these are divided into three distinct classes. Firstly, the self splicing introns that fall into groups I and II respectively depending on their structure and the recognition sequences. Self splicing group I intron was the first ribozyme to b... ...the cells, the localisation of the ribozymes in the cells as well as the selection site of the messengerRNA (James and Gibson, 1998). Ribozymes are currently considered to hold many promises for the future development of gene therapy as they have the ability to splice and cleave any target RNA sequences. There are seven natural ribozymes known and several artificial ribozymes have been created. These artificial ribozymes are being used as therapeutic agent to target the aberrant gene expression in many lethal diseases such as cancer. The limitation of artificial ribozymes is mainly due to the difficulty in their delivery to the target cells. Therefore, more research needs to be conducted in thoroughly studying the organisation and structures of the natural RNA ribozymes to achieve successful artificial ribozymes that have complex function in the future.

Wednesday, January 15, 2020

American Art Project Essay

It is believable that John Vanderlyn, in his painting Landing of Columbus, was trying to portray the success of Columbus and his crew. Columbus heroic stance and elegant expression are made all the more impressive in comparison to the native people who witness the event. The Native Americans are naked, fearful or subservient, bowing down before the explorer in awe and reverence. The symbols of empire are shown in the heroic explorer with his Christian crosses and steel swords symbolizing the significance in the power of civilization. In 1836 of June, Congress had commissioned John Vanderlyn to paint the Landing of Columbus. About eleven years later the painting was hung in the Rotunda by January 1847. Expansion was an overwhelming preoccupation in nineteenth-century America, but it was by no means the only cultural preoccupation. The subject of the painting, foregrounding the ambiguous meeting of two cultures, provided a space for artists to work out many central issues, for example, how to reconcile Indian Removal with notions of the Noble Savage. Another way is how to remake a country torn apart by sectional strife. The following settlements and expansions span the period from 1835 to 1912. Americans had a chaotic eighty-year period that witnessed the filling of Americas geographical borders, the bloody anguish of the Civil War, the horror of slavery in America, the overthrow of Native peoples, and many more events pertaining to the expansion. Vanderlyns painting contains images of contact between European explorers and Native Americans. He clearly shows a representation of what many of the settlements contained and how frightened the Natives were. John Trumbulls painting of the Declaration of Independence depicts the signing of the declaration by forty-two out of the fifty-six and five patriots. It is believed that Trumbull was paid to paint Jeffersons foot on top of Adams foot to illustrate that Jefferson dominated Adams. However, as time passed, the painting had been exposed to smoke, dirt, humidity, and other elements. Before modern art preservation was mastered, the painting had been repainted to repair damaged areas. The repairing is what changed the shape of Jeff ersons foot to look as though it was on Adams foot. The painting of the Declaration of Independence was commissioned by Congress in1817, but the painting was not hung until October 5, 1818. There were no major events recorded during the time of Trumbulls painting. However there were many  questions being asked about what compelled Trumbull to paint the scene inaccurately Trumbulls depiction was not to paint the scene correctly, but to show value of the document and its sacred place in our nations history. He wanted to capture the real meaning of the Declaration of Independence and the men who wrote and signed it. It is promising that John Trumbull did a very good job at communicating his message through context and content. Similar to Trumbulls Declaration of Independence, the General George Washington Resigning His Commission painting features an arrangement of characters with figures standing and seated in the background. Also, in the central action being the transfer of documents, George Washington is standing in the center showi ng the democratic ideal shared between the two paintings. Furthermore, the addition of a draped cloak over Washingtons chair is reminiscent of a kings robe over a throne. This symbolization is of Washingtons retirement from rule and establishing civilian authority over the military. Trumbulls painting General George Washington Resigning His Commission was commissioned in 1817 and hung in 1824. Many events have occurred during this time, however, none pertain to Trumbulls painting. On the other hand, the painting depicts Washington submitting his resignation as Army Commander-in-Chief to the Congress on December 23, 1783. Washington stands in the center of the room at the Maryland State House in Annapolis, where Congress was meeting at the time, and addresses the president of the Congress. Trumbull, although he added extra people in his painting, depicted a clear message about George Washington and his resignation. The Embarkation of the Pilgrims by Robert Weir affects many people with the upsetting feeling many get from reading the words of one of the Pilgrims, We sang psalms and were merry. The painting is gloomy, hard and uninteresting, but depicts the respect of the general public because of its deep religious spirit. Also, because of the clever handling of shadowing and general carefulness, the painting has an admirable technique. In 1836, the United States government commissioned Robert W. Weir to paint the Embarkation of the Pilgrims and hung in 1843. The Mexican war was an event that inspired Weirs painting. The moral and geographic greatnesses were absolutely holey understandings. In other words, when the land was conquered through an event like the Mexican War, it was ultimately acceptable by the righteous promise of the Embarkation. The painting represents significant  historical moments leading to the founding of the American Republic. The painting clearly depicts the Pilgrim families gathered around their pastor, John Robinson, for a farewell service on the deck of the Speedwell before its departure from Holland. Thomas Hart Benton, Missouri Benton was born on March 14, 1782, in Hillsboro, North Carolina. When his family migrated to Tennessee his father had died, and as a young man, was left in charge of significant land holdings. Benton, who established a law practice, also served as a colonel in th e War of 1812 under General Andrew Jackson. He practiced law and edited the second newspaper west of the Mississippi after moving to St. Louis, Missouri in 1815. In 1820, Benton ran for Senate with the interests of bettering the western territories. His support of the anti-United States Bank earned him support. However, Bentons anti-slavery views cost him the seat as Senate. In 1852 Benton was elected to the House of Representatives, but only served one term. Benton had written Thirty Years from 1855 to 1858 and Abridgement of Debates of Congress from 1789 to 1856. Benton Died on April 10, 1858. Personaly, Thomas Benton is a good choice to represent the stateof Missouri. However, he should have thought carefully about the slavery terms. Francis Blair, Missouri Francis Blair, born on February 19, 1821, in Lexington, Kentucky, attended schools in Washington, D.C. and graduated from Princeton University in 1841. Most importantly Blair had studied law at Transylvania University. In 1842he went on to practice in St. Louis, Missouri. During the Mexican War, Blair was selected as attorney general for the New Mexican Territory. He was also a personal friend of Thomas Benton. The only difference between the two men is that Benton was for slavery and Blair was against it. Blair, in 1852, was elected to the U.S. House of Representatives. However, he was defeated in 1858. In 1860 he was reelected into the House. During he Civil War Benton served as a major general, and in 1861, was saved Missouri for the Union. Unfortunately, his helping with the Union left him broke and unsuccessful for election as vice president in 1868. In 1871 he was, however, was chosen to become the United States Senator. Blair died from paralysis on July 9, 1875. Blair, better than Benton, is a great representative for Missouri because of his heart for the state and the people. Bibliography Atkins, Scott. The Pilgrims in the Capitol. Virginia.edu. February 25, 2014. Accessed February 25, 2014. http//xroads.virginia.edu/cap/puritan/purrot.html. Francis Preston Blair. Architect of the Capitol. February 25, 2014. Accessed February 25, 2014. http//www.aoc.gov/capitol-hill/national-statuary-hall-collection/francis-preston-blair. General George Washington Resigning His Commission. Learn NC. February 25, 2014. Accessed February 25, 2014. http//www.learnnc.org/lp/multimedia/6288. Parker, Edgar. Embarkation of the Pilgrims. Pilgrim Hall Museum. February 25, 2014. Accessed February 25, 2014. http//www.pilgrimhallmuseum.org/ce_history_paintings.htm. Swislocki, Allie and Joanna Hallac. Trumbulls Declaration of Independence Fact orFiction Blog, November 04, 2011. Accessed February 25, 2014. http//uschs.wordpress.com/2011/11/04/trumbulls-declaration-of-independence-fact-or-fiction/ The Embarkation of the Pilgrims. book dome. February 25, 2014. Accessed February 25, 2014. http//bookdome.com/architecture/National-Capitol/The-Embarkation-Of-The-Pilgrims.html. Thomas Hart Benton. Architect of the Capitol. February 25, 2014. Accessed February 25, 2014. http//www.aoc.gov/capitol-hill/national-statuary-hall-collection/thomas-hart-benton. Truettner, William H. Prelude to Expansion Repainting the Past. In West as America Reinterpreting Images on the Frontier, 1820-1920, edited by William H. Trumbulls Old Senate Chamber. Marylands Old Senate Chamber. September 21, 2012. Accessed February 25, 2014. http//marylandstatehouse.blogspot.com/2012/09/trumbulls-old-senate-chamber.html. Truettner, Prelude to Expansion, 55-95 and Vivian Green Fryd, Art Empire The Politics of Ethnicity in the United States Capitol, 1815-1860 (New Haven and London Yale University Press, 1992). Allie Swislocki and Joanna Hallac, Trumbulls Declaration of Independence Fact orFiction Blog, November 04, 2011. Accessed February 25, 2014. HYPERLINK http//uschs.wordpress.com/2011/11/04/trumbulls-declaration-of-independence-fact-or-fiction/http//uschs.wordpress.com/2011/11/04/trumbulls-declaration-of-independenc e-fact-or-fiction/. Trumbulls Old Senate Chamber, Marylands Old Senate Chamber, September 21, 2012, accessed February 25, 2014, http//marylandstatehouse.blogspot.com/2012/09/trumbulls-old-senate-chamber.html. General George Washington Resigning His Commission, Learn NC, February 25, 2014, accessed February 25, 2014, http//www.learnnc.org/lp/multimedia/6288. The Embarkation of the Pilgrims, book dome, February 25, 2014, accessed February 25, 2014, http//bookdome.com/architecture/National-Capitol/The-Embarkation-Of-The-Pilgrims.html. Atkins, Scott, The Pilgrims in the Capitol, Virginia.edu, February 25, 2014, accessed February 25, 2014, http//xroads.virginia.edu/cap/puritan/purrot.html. Edgar Parker, Embarkation of the Pilgrims, Pilgrim Hall Museum, February 25, 2014, accessed February 25, 2014, http//www.pilgrimhallmuseum.org/ce_history_paintings.htm. Thomas Hart Benton, Architect of the Capitol, February 25, 2014, accessed February 25, 2014, http//www.aoc.gov/capitol-hill/national-statuary-hall-collection/thomas-hart-benton. Francis Preston Blair, Architect of

Tuesday, January 7, 2020

Breast Cancer Screening - 1787 Words

An analysis of the effectiveness of population-based screening for breast cancer. Breast cancer is the leading cause of death due to cancer in women, with statistics from the USA showing that one in eight women will develop the disease.1 Studies in the UK show that 90% of women diagnosed in the early stages survive the disease, while this figure is only 15% if diagnosed at a later stage illustrating the importance of an effective screening programme to reduce mortality.2 In the following essay I will review various randomised control studies and cohort studies in order to establish how nationwide screening programmes best reduce mortality, looking at the targeted sector of the population and the methods in practice. I will also address†¦show more content†¦With the majority of tumours being slow growing it has been established from various studies that biennial screening is the most effective time frame. This is due to the identification of slow growing tumours at an early enough stage for recovery and at the same time ensures a reduced rate of false-posi tives compared to annual mammograms.5 â€Å"In addition, since the proportion of DCIS is highest in younger women, screen detection of DCIS that may not be clinically signiï ¬ cant could be considered a further harm.†5 Therefore it is the woman’s prerogative whether the risk of cancer outweighs the possibility of coming into contact with the aforementioned harms. With the implementation of mammograms as a population based screening program the targeted population must be scrutinised, because although it is common practice for women over 40 to be covered by health insurance for mammograms there are increasing numbers of women below that age with breast cancer.Show MoreRelatedAn Invitation For Breast Cancer Screening923 Words   |  4 Pagesinvitation for breast cancer screening Body Global incidence - cancer as a second most common type of cancer -high rate of breast cancer in high income countries Breast compression - why is necessary, mammography process explanation Risk factors – age - cancer increases with age and why -genetic factor-breast cancer in the family Advantages of breast cancer screening - effective method, non-invasive Conclusion Breast screening=early detection=Read MoreThe Ethical Phenomenon Of Breast Cancer Screening And Treatments867 Words   |  4 Pagesboth the BRCA1 and BRCA 2 gene mutations and choosing bilateral mastectomies for early-stage breast cancers (Weintraub, 2015). 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Annually, more than 200,000 American women suffer from breast cancer and approximatelyRead MoreAccessibility Of Services As Facilitating Factors1401 Words   |  6 Pagesdefined as those factors related to the availability of screening services to participants. Good accessibility of services was seen as a facilitating factor for screening, under the general theme of government and community support. Issues related to this category included a women’s insurance status, the availability of affordable screening services, particularly mass screening projects at the workplace, and having adequate transportation to screening sites (Hatefnia et al., 2010). Accessibility of servicesRead MoreLets Stay Abreast Program Paper1589 Words   |  7 Pages The â€Å"Let’s Stay Abreast Program† focus is to plan, promote, and implement a program that will educate and provide screening to help decrease the incidence and reduce mortality of breast cancer, through early detection among women in Co-Op, Bronx, New York. In 2016, 91 million was spent on Governor Cuomo’s initiative to increase breast cancer awareness and screening by focusing on providing public awareness campaign, community outreach programs, patient navigators, and mobile mammography vans (Governor